Peptide drugs have the advantages of clear targets and good drug properties, and have become one of the hot spots in new drug research. At present, globally approved polypeptide drugs have been widely used in many treatment fields such as metabolism and endocrine system, immune system, and musculoskeletal system. In particular, the popular weight-loss drugs of semiglutide and tierpositide in the past two years. The market demand is growing steadily and has huge potential for future development.

Although polypeptide drugs have low membrane permeability, short half-lives, and rapid elimination in vivo, new modification and production technologies have enabled the development of polypeptide drugs to overcome various difficulties. In addition, emerging technologies such as artificial intelligence, high-throughput, and informatization have also made great progress in the development of polypeptide drugs in terms of target discovery, peptide library establishment, process development, characterization, and entire process management.

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Author: spike

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