随着人工智能（AI）技术的发展，人工智能药物发现与设计（AIDD）正在成为生物医药产业的新热点方向。AIDD通过自适应学习大幅缩短了药物研发周期与成本，尤其在靶点验证、Hit发现以及Lead优化等方面发挥了重要作用。虽然仍然依赖湿实验，但高通量生物膜干涉（BLI）技术可以辅助其进行快速验证。BLI技术摆脱了传统复杂的流路系统，实现了快速、直接的分子相互作用检测。通过BLI技术，研究人员可以在微孔板中实时监测分子之间的相互作用，从而高效验证潜在药物候选物。这种“湿实验”的高通量化不仅加速了药物研发过程，还为“设计- 检测-优化”提供了更完善的闭环。AI技术与BLI技术的结合将进一步推动药物研发的创新与发展。 Poke me to sign up

Live broadcast time: April 2, 2024 19:00-20:30

The content outline is as follows:

Topic 1:Application of high-throughput BLI technology in large-scale screening of biopharmaceuticals

keynote speaker:Sun Xiaoxiang/Doctor

Senior Researcher, Department of Protein Science, WuXi Biotech

1. In the early research stage of drug discovery, the importance of large-scale screening for active or strongly binding molecules

2. Current screening technology:The importance, principles, technical advantages and applications of the binding assay

3. case analysis:Screening of antigen-antibody and high-fever miniprotein molecules

Problem 2:Application of high-throughput BLI in AI drug manufacturing

keynote speaker:Wang Guoqiang/Doctor

Small Crocodile Biological North District Promotion Manager

1. Current status of application of AI in drug discovery

2. Combination case of BLI technology and AI manufacturing

3. Introduction to BLI technical principles

4. Introduction of the new generation of high-throughput BLI equipment

Introduction to the lecturer

** Sun Xiaoxiang| Dr.
**

Senior Researcher, Department of Protein Science, WuXi Biotech毕业于同济大学，参与多项抗体药物活性及成药性分析项目。

Wang Guoqiang| Dr.

Small Crocodile Biological North District Promotion Manager

Graduated from China Agricultural University with a doctorate in his research direction on protein structure and function. He has worked in well-known companies such as NanoTemper Company in Germany, Nexcelom Company in the United States and PerkinElmer Company in the United States, and is familiar with various protein analysis and molecular interaction technologies. He currently works for GatorBio (Crocodile Biology) and is responsible for the promotion of Gator series of molecular interaction products.

Registration/viewing method： Poke me to sign up

Computer viewing link **: https://dx5.cn/4vevJg ※ *(Copy the link to the browser to open)

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about the company

Gator Bio is a leading global bioanalytical technology company operating in Silicon Valley, Shanghai, Suzhou and other places. The company is committed to developing, manufacturing and selling innovative bioanalytical equipment, software, biosensors, specialized consumables and reagents to help scientists in biopharmaceutical and life sciences complete their work better, faster and more efficiently.

The Gator® series of analytical instruments is based on the new generation of Biolayer Interferometry (BLI) technology. It calculates various biological reaction parameters by collecting and analyzing changes in the reflection spectrum of the optical fiber biosensor surface, such as antibody titer determination, dissociation constant sequencing, affinity constant determination, epitope grouping, AAV capsid titer and empty shell rate detection, LNP titer and kinetic detection, etc.

Gator® BLI technology has been widely used in North America, Europe and the Asia-Pacific region, and is highly recognized by scientists around the world.